生物学概念与途径课件下载_RAOLAB

生物学概念与途径课件下载

第一章孤独的天才

1A 一意孤行的伯乐

1B 达尔文的泛生假说

第二章遗传与染色体

2A 老兵不死：百年亿蝇为哪般？

第三章遗传信息的载体： DNA

第四章遗传密码

第五章细胞间相互作用：胚胎诱导

第六章发育的基因调控

第七章我与非我

第八章多样性：免疫球蛋白

第九章电传导

第十章化学传递

第十一章还原与整合

第十二章药物与生物

第十三章遗传筛选

第十四章分子生物学筛选

14A 美丽的荧光蛋白

第十五章生物化学分离纯化

15A神经生长因子

第一章

Mendel G (1866) Experiments in Plant Hybridization. Verhand- lungen des naturforschenden Vereines in Brünn, Bd. IV für das Jahr, Abhandlungen, 3-47(Experiments in Plant Hybridization in Genetics: readings from Scientific American pp. 8-17. W.H. Freeman and Company, San Francisco-USA)

第二章

Morgan TH (1910) Sex linked inheritance in Drosophila. Science 32:120-122.

Sturtevant AH (1913) The linear arrangement of six sex-linked factors in Drosophila as shown by mode of association. Journal of Experimental Zoology 14:39-45.

第三章

Griffith F (1928) The significance of pneumococcal types. Journal of Hygiene 27:113-159.

Avery OT, MacLeod CM and McCarty M (1944) Studies on the chemical nature of the substance inducing transformation of pneumococcal types. Journal of Experimental Medicine 79: 137-158.

第四章

Brenner S (1957) On the impossibility of all overlapping triplet codes in information transfer from nucleic acid to proteins. Proceedings of the National Academy of Sciences USA 43:687-694.

Lengyel P, Speyer JF, Ochoa S (1961) Synthetic polynucleotides and the amino acid code. Proceedings of the National Academy of Sciences USA 47:1936-1942.

第五章

Spemann H and Mangold H (1924) Über Induktion von Embryonalanlagen durch, Implantation artfremder Organisatoren. Archive für Mikroskopische Anatomie Entwicklungsmechanik 100:599-638. (translated as Spemann H and Mangold H (2001). Induction of embryonic primordia by implantation of organizers from a different species. International Journal of Developmental Biology 45:13-38).

Nieuwkoop PD (1969) The formation of the mesoderm in urodelean amphibians. I. Induction by the endoderm. Wilhelm Roux’ Archive of Developmental Biology 162:341-373.

第六章

Lewis EB (1978) A gene complex controlling segmentation in Drosophila. Nature 276:565–570.

Nüsslein-Volhard C and Wieschaus E (1980) Mutations affecting segment number and polarity in Drosophila. Nature 287:795–801.

第七章

Behring E and Kitasato S (1890) Über das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei Thieren. Deutsche medizinische Wochenschrift 16:1113-1114 (The mechanism of immunity in animals to diphtheria and tetanus).

Landsteiner K (1901) Über Agglutinationserscheinungen normalen menschlichen Blutes. Wiener Klinische Wochenschrift 14:1132-1134. (On the agglutination of normal human blood).

第八章

Burnet F (1957) A modification of Jerne’s theory of antibody production using the concept of clonal selection. Australian Journal of Science 20:67-69.

Hozumi N and Tonegawa S (1976) Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proceedings of the National Academy of Sciences USA 73:3628-3632.

第九章

Curtis HJ and Cole KS (1940) Membrane action potentials from the squid giant axon. Journal of Cellular and Comparative Physiology 15:147-157.

Hodgkin AL and Huxley AF (1952a) Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. Journal of Physiology 116:449–472.

第十章

Elliot TR (1905) On the action of adrenalin. Journal of Physiology 32:401-467.

Dale HH, Feldberg W and Vogt M (1936) Release of acetylcholine at voluntary motor nerve endings. Journal of Physiology 86: 353-380.

第十一章

Nathans J, Piantanida TP, Eddy RL, Shows TB and Hogness DS (1986) Molecular genetics of inherited variation in human color vision. Science 232:203-210.

Hubel DH and Wiesel TN (1962) Receptive fields, binocular interaction and functional architecture in the cat’s visual cortex. Journal of Physiology 160:106-154.

第十二章

Fleming A (1929) On the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae. British Journal of Experimental Pathology 10:226-236.

Liu, J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, Schreiber SL (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807-15

第十三章

Konopka RJ and Benzer S (1971) Clock mutants of Drosophila melanogaster. Proceedings of the National Academy of Sciences USA 68:2112-2116.

Vitaterna MH, King DP, Chang A-M, Kornhauser JM, Lowrey PL, McDonald JD, Dove WF, Pinto LH, Turek FW and Takahashi JS (1994) Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264:719-725.

第十四章

Schatz DG, Oettinger MA and Baltimore D (1989). The V(D)J recombination activating gene, RAG1. Cell 59:1035-1048.

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA and Charpentier E (2012). A programmable dual-RNA-guided DNA endoclease in adaptive bacterial immunity. Science 337:816-821.

第十五章

Vale RD, Reese TS and Sheetz MP (1985). Identification of a novel force-generating protein, kinesin, involved microtubule-based motility. Cell 42:39-50.

Prusiner SB, Groth DF, Cochran SP, Masiarz FR, McKinley MP and Martinez HM (1980). Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent. Biochemistry 21:4883-91.

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